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Stem cell therapy, primarily bone marrow transplantation, plays a key role in treating leukemia and other types of cancer. To better track the fate of stem cells injected into patients, researchers have turned to a combination of fluorine-based magnetic resonance imaging (MRI) and nanoparticles made of liquid perfluorocarbons. The team described its use of two distinct perfluorocarbon nanoparticles to track different stem cells injected into tumor-bearing mice. These particular nanoparticles are taken up readily by stem cells over the course of a 12-hour incubation, and the stem cells showed no ill effects from the nanoparticles.
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