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An RNA-binding protein that is overproduced in ovarian cancer may present a new target for diagnosis or treatment of ovarian and other cancers.
Knocking down PTB expression with small, interfering RNA "substantially impairs ovarian tumor cell growth, colony formation and invasiveness."
Ovarian cancer is commonly referred to as "the silent killer," as it usually is not discovered until its advanced stages. One woman in 58 will develop ovarian cancer during her lifetime.
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