Studies Show Geron's Stem Cell Therapeutic For Spinal Cord Injury Produces Nerve Growth Factors

Geron reported that GRNOPC1, the company’s human embryonic stem cell (hESC)-based oligodendroglial progenitor therapeutic, produces multiple nerve growth factors, proteins that stimulate the survival and regeneration of neurons damaged during spinal cord injury. The studies describe a newly discovered neurotrophic effect that, in addition to the previously documented in vivo remyelinating activity of these cells, serves as a second mechanism of action that demonstrates the product’s beneficial effects when injected into animal models of acute spinal cord injury.